Structural Biology: Parkin’s Serpentine Shape Revealed in the Year of the Snake

نویسندگان

  • Katja K. Dove
  • Rachel E. Klevit
چکیده

Parkin is an E3 ubiquitin ligase, mutations in which are responsible for autosomal recessive juvenile parkinsonism. Recently, several structures of Parkin have been solved, revealing its serpentine shape and modes of auto-inhibition.

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عنوان ژورنال:
  • Current Biology

دوره 23  شماره 

صفحات  -

تاریخ انتشار 2013